Oligonucleotide microarray (DNA chip)–based hybridization analysis is a promising new technology which potentially allows rapid and cost–effective screens for all possible mutations and ...

Abstract Purpose: To demonstrate the accuracy and sensitivity of Representational Oligonucleotide Microarray Analysis (ROMA) to describe copy number changes in patients with chromosomal abnormalities.

Patients and Methods Two hundred fifty-one neuroblastoma specimens were analyzed using a customized oligonucleotide microarray comprising 10,163 probes for transcripts with differential expression in ...

For most researchers DNA microarrays are synonymous with high-throughput gene expression analysis. But they also are invaluable genotyping tools. Now that the International HapMap Project (see article ...

A new platform for making oligonucleotides offers chemists a way to plug in five types of nucleoside connections, so they can tailor properties of oligonucleotide therapeutics. These short DNA or ...

Agilent Technologies Inc. has announced the availability of oligo array-based comparative genomic hybridization (Oligo aCGH) microarrays with a five-fold increase in density over previous offerings ...

DNA microarray analysis was first described in the mid-1990s as a means to probe the expression of thousands of genes simultaneously 1,2 and was quickly adopted by the research community for the ...

Courtesy of CombiMatrix A number of companies are using the lessons and technologies of traditional genomics--the microarray chief among them--to delve into the more challenging world of functional ...

The advent of microarray technology has a much longer history than many realize. Ask any scientist “What is a microarray?” and the overwhelming majority will describe some form of glass or ...