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A plethora of studies have documented that gene expression profiling using DNA microarrays for various types of hematological malignancies provides novel information, which may have diagnostic and ...
DNA microarrays might also facilitate the functional analysis of new anti-cancer compounds and the identification of novel biomarkers and molecular-imaging probes.
The DNA copy that is made, called complementary DNA (cDNA), is then applied to the microarray. The cDNA binds to complementary base pairs in each of the spots on the array, a process known as ...
“Choosing the DNA source and microarray type depends on the chromosomal changes and resolution that are to be detected by the assay,” said Todd Martinsky, executive vp, TeleChem International ...
Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...
Chips containing orderly arrays of thousands of DNA sequences--so-called DNA microarrays--have become an indispensable part of the biologist's tool kit for studying gene expression and gene ...
Microarray technology is increasingly being compared and contrasted to NGS. NGS evolved as a group of new, high-throughput DNA sequencing technologies that dramatically reduced sequencing costs.
A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in studies of multiple ...
Lei Zhang, Thomas Hurek, Barbara Reinhold-Hurek, A nifH-Based Oligonucleotide Microarray for Functional Diagnostics of Nitrogen-Fixing Microorganisms, Microbial Ecology, Vol. 53, No. 3, Microbial ...
image: DNA microarrays can be easily interrogated with only the naked eye using a new electrostatic imaging technique developed in the laboratory of Jay Groves, a chemist with Berkeley Lab, UC ...
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