DNA damage. A series of Reviews on the pathways that detect and repair different types of DNA damage.

New research discovered a key protein that plays a role in DNA double-strand break repair. MSH2-MSH3, a mismatch repair protein, is recruited to DSB sites through the interaction with a chromatin ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these ...

Scientists discovered that a well-known DNA repair pathway, the Fanconi anemia pathway, surprisingly plays a key role in repairing double-strand DNA breaks created by CRISPR-Cas9. It acts as a ...

RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...

Now, a team at Harvard Medical School has identified a novel mechanism of DNA repair that occurs exclusively in neurons, some of the longest-lived cells in the body.

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

DNA replication and repair are critical processes that ensure the correct genetic material of a biological system is carried on. DNA continually undergoes a process of replication and division and ...

New research on the International Space Station has increased astronauts' knowledge of DNA repair in space.

Cellular DNA is subjected to continual attack, both by reactive species inside cells and by environmental agents. Toxic and mutagenic consequences are minimized by distinct pathways of repair, and 130 ...

Over time, DNA mutations add up, which can eventually trigger cancer. A recent study investigated the cell's own DNA-fixing mechanisms.