Takehiko Shibata, Taro Nishinaka, Tsutomu Mikawa, Hideki Aihara, Hitoshi Kurumizaka, Shigeyuki Yokoyama, Yutaka Ito, Homologous Genetic Recombination as an Intrinsic Dynamic Property of a DNA ...

The transcription-independent function of p53 facilitates DNA repair and controls recombination. p53 facilitates base-excision repair (BER) mainly via association with BER components. For example ...

Homologous recombination maintains genome stability in mammalian mitotic cells through precise repair of DNA double-strand breaks and other lesions that occur during normal cellular metabolism and ...

Site-specific genetic recombination promoted in vivo by the EcoRI endonuclease has been demonstrated by using constructed hybrid plasmids in which the chloramphenicol resistance gene was inactivated ...

Genetic recombination is the transmission-genetic process by which the combinations of alleles observed at different loci in two parental individuals become shuffled in offspring individuals. In ...

Homologous DNA recombination The most important form of genetic recombination is homologous recombination. The process involves the basic facts such as two double double-stranded DNA molecules ...

One type of genetic mutation may, therefore, be related to certain aspects of human development, the researchers suggested. When the scientists examined genetic sequences from Alzheimer's and ...

Belgian researchers from VIB-KU Leuven Center for Microbiology and VIB-UGent Center for Plant Systems Biology have developed a new toolbox of 16 different short DNA sequences that allow triggering ...

Scientists have discovered that the RecA family recombinases function as a new type of rotary motor proteins to repair DNA damages. Homologous recombination (HR) is a mechanism that repairs ...

Biodiversity is disappearing at an alarming rate and is driven by human activity: contamination, greenhouse gases and extreme temperatures. But how exactly do these factors affect the reproduction and ...

In the context of the NIH Guidelines for Research Involving Recombinant DNA Molecules, recombinant DNA molecules are defined as either: molecules that are constructed outside living cells by joining ...